View source for 8xxl


==Cryo-EM structure of the human 40S ribosome with PDCD4==
<StructureSection load='8xxl' size='340' side='right'caption='[[8xxl]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xxl]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XXL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xxl OCA], [https://pdbe.org/8xxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xxl RCSB], [https://www.ebi.ac.uk/pdbsum/8xxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xxl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RS32_HUMAN RS32_HUMAN] Component of the small ribosomal subunit (Probable) (Ref.8). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase II alpha by CKII (PubMed:9299532).<ref>PMID:23636399</ref> <ref>PMID:9299532</ref> [REFERENCE:8]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cheng J]]
[[Category: Huang Z]]
[[Category: Li Y]]
[[Category: Wang M]]
[[Category: Ye X]]