View source for 8xy2


==Crystal structure of MPXV P1 protein S87P mutant==
<StructureSection load='8xy2' size='340' side='right'caption='[[8xy2]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xy2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XY2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xy2 OCA], [https://pdbe.org/8xy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xy2 RCSB], [https://www.ebi.ac.uk/pdbsum/8xy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xy2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PG035_MONPV PG035_MONPV] Bcl-2-like protein which contributes to virulence by preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B.[UniProtKB:P17361]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Monkeypox virus]]
[[Category: Lei J]]
[[Category: Ni XC]]