View source for 8yec


==Crystal structure of L-ribulose 3-epimerase in complex with D-allulose==
<StructureSection load='8yec' size='340' side='right'caption='[[8yec]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8yec]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YEC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUD:D-FRUCTOSE'>FUD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PSJ:D-PSICOSE'>PSJ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yec OCA], [https://pdbe.org/8yec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yec RCSB], [https://www.ebi.ac.uk/pdbsum/8yec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yec ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KET3E_ARTGO KET3E_ARTGO] Catalyzes the reversible C-3 epimerization of several ketoses. Shows the highest enzymatic activity for the epimerization of L-ribulose to L-xylulose. Is also able to convert D-allulose (also known as D-psicose) to D-fructose and, to a lesser extent, L-tagatose to L-sorbose, D-ribulose to D-xylulose, L-allulose to L-fructose and D-tagatose to D-sorbose.<ref>PMID:27713017</ref> <ref>PMID:30279320</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arthrobacter globiformis]]
[[Category: Large Structures]]
[[Category: Mine S]]
[[Category: Nakamichi Y]]
[[Category: Watanabe M]]