View source for 8yi6


==BesA wild-type from Streptomyces cattleyicolor==
<StructureSection load='8yi6' size='340' side='right'caption='[[8yi6]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8yi6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_cattleya Streptomyces cattleya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YI6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yi6 OCA], [https://pdbe.org/8yi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yi6 RCSB], [https://www.ebi.ac.uk/pdbsum/8yi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yi6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BESA_STREN BESA_STREN] Involved in the biosynthesis of terminal alkyne-containing amino acids such as L-beta-ethynylserine, that are produced as antibiotics by S.cattleya. Catalyzes the ATP-dependent ligation of L-propargylglycine to L-glutamate to form the dipeptide L-gamma-glutamyl-L-propargylglycine. Is selective for L-propargylglycine over norvaline, allylglycine and the standard proteinogenic amino acids, except L-cysteine which can be used as a substrate to a lesser extent.<ref>PMID:30867596</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces cattleya]]
[[Category: Fujishiro T]]