View source for 8ynt


==Cryo-EM structure of SNAP-94847-bound MCHR1, S2 state==
<StructureSection load='8ynt' size='340' side='right'caption='[[8ynt]], [[Resolution|resolution]] 3.43&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ynt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Pan_paniscus Pan paniscus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YNT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.43&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1D6T:~{N}-[3-[1-[[4-[3,4-bis(fluoranyl)phenoxy]phenyl]methyl]piperidin-4-yl]-4-methyl-phenyl]-2-methyl-propanamide'>A1D6T</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ynt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ynt OCA], [https://pdbe.org/8ynt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ynt RCSB], [https://www.ebi.ac.uk/pdbsum/8ynt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ynt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/A0A2R9AFP0_PANPA A0A2R9AFP0_PANPA] [https://www.uniprot.org/uniprot/MCHR1_HUMAN MCHR1_HUMAN] Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.<ref>PMID:10421367</ref> <ref>PMID:15340116</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Pan paniscus]]
[[Category: Synthetic construct]]
[[Category: Gong W]]
[[Category: Li X]]
[[Category: Liu G]]
[[Category: Liu H]]
[[Category: Ye X]]