View source for 8yo7


==structure of phage T6 topoisomerase II central domain bound with DNA and m-AMSA==
<StructureSection load='8yo7' size='340' side='right'caption='[[8yo7]], [[Resolution|resolution]] 3.16&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8yo7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/DNA_molecule DNA molecule], [https://en.wikipedia.org/wiki/Enterobacteria_phage_T6 Enterobacteria phage T6] and [https://en.wikipedia.org/wiki/Escherichia_phage_T4 Escherichia phage T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YO7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.16&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASW:N-[4-(ACRIDIN-9-YLAMINO)-3-METHOXYPHENYL]METHANESULFONAMIDE'>ASW</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yo7 OCA], [https://pdbe.org/8yo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yo7 RCSB], [https://www.ebi.ac.uk/pdbsum/8yo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yo7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TOP5_BPT4 TOP5_BPT4] Medium subunit of the DNA topoisomerase that untwists superhelical DNA. Controls topological states of double-stranded DNA by transient breakage and subsequent rejoining of DNA strands.<ref>PMID:226976</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: DNA molecule]]
[[Category: Enterobacteria phage T6]]
[[Category: Escherichia phage T4]]
[[Category: Large Structures]]
[[Category: Chen YT]]
[[Category: Xian RQ]]
[[Category: Xin YH]]