View source for 8yqy


==ASFV RNA polymerase-M1249L complex complete==
<StructureSection load='8yqy' size='340' side='right'caption='[[8yqy]], [[Resolution|resolution]] 3.68&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8yqy]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/African_swine_fever_virus African swine fever virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YQY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.68&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yqy OCA], [https://pdbe.org/8yqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yqy RCSB], [https://www.ebi.ac.uk/pdbsum/8yqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yqy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A3S7XUW7_ASF A0A3S7XUW7_ASF] Catalytic component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity). Forms the polymerase active center together with RPB2 (By similarity). Part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template.[ARBA:ARBA00029401]  DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[RuleBase:RU004279]
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</StructureSection>
[[Category: African swine fever virus]]
[[Category: Large Structures]]
[[Category: Feng XY]]