View source for 8yx6


==Structure of a Cys-loop Receptor in Zinc Binding State==
<StructureSection load='8yx6' size='340' side='right'caption='[[8yx6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8yx6]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YX6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yx6 OCA], [https://pdbe.org/8yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/8yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yx6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZACN_HUMAN ZACN_HUMAN] Ligand-gated cation channel that allows the movement of sodium and potassium monoatomic cations across cell membranes when activated by zinc (Zn2+), copper (Cu2+), and changes in pH (PubMed:26872532). Could also transport cesium (PubMed:26872532).<ref>PMID:26872532</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lu XH]]
[[Category: Shen YQ]]
[[Category: Yang X]]