View source for 8z5m


==human phosphorylase kinase alpha/gamma/delta subcomplex - inactive state==
<StructureSection load='8z5m' size='340' side='right'caption='[[8z5m]], [[Resolution|resolution]] 3.66&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8z5m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z5M FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.66&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z5m OCA], [https://pdbe.org/8z5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z5m RCSB], [https://www.ebi.ac.uk/pdbsum/8z5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z5m ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/KPB1_HUMAN KPB1_HUMAN] Glycogen storage disease due to muscle phosphorylase kinase deficiency. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/KPB1_HUMAN KPB1_HUMAN] Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ma R]]
[[Category: Yan K]]