View source for 8zar


==EmrAB-TolC MFS-type tripartite multidrug efflux pump FA==
<StructureSection load='8zar' size='340' side='right'caption='[[8zar]], [[Resolution|resolution]] 3.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8zar]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZAR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.59&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zar OCA], [https://pdbe.org/8zar PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zar RCSB], [https://www.ebi.ac.uk/pdbsum/8zar PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zar ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EMRA_ECOLI EMRA_ECOLI] Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC.<ref>PMID:12482849</ref> <ref>PMID:1409590</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Du D]]
[[Category: Tuerxunjiang M]]
[[Category: Zhong Z]]