View source for 8zfl


==Caenorhabditis elegans ACR-23 in apo state==
<StructureSection load='8zfl' size='340' side='right'caption='[[8zfl]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8zfl]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans] and [https://en.wikipedia.org/wiki/Shimwellia_blattae Shimwellia blattae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZFL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zfl OCA], [https://pdbe.org/8zfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zfl RCSB], [https://www.ebi.ac.uk/pdbsum/8zfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zfl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/ACH23_CAEEL ACH23_CAEEL] Betaine receptor that functions as a ligand-gated non-selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA.<ref>PMID:23950710</ref> <ref>PMID:24212673</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Large Structures]]
[[Category: Shimwellia blattae]]
[[Category: Chen QF]]
[[Category: Gong HH]]
[[Category: Guo F]]
[[Category: Li TY]]
[[Category: Liu FL]]
[[Category: Liu S]]