View source for 8zgw


==Drimenyl diphosphate synthase SsDMS_F248Y&D303E from Streptomyces showdoensis in complex with farnesyl diphosphate (FPP) and Mg2+==
<StructureSection load='8zgw' size='340' side='right'caption='[[8zgw]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8zgw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_showdoensis Streptomyces showdoensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZGW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zgw OCA], [https://pdbe.org/8zgw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zgw RCSB], [https://www.ebi.ac.uk/pdbsum/8zgw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zgw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DMS_STREW DMS_STREW] Catalyzes the cyclization of farnesyl diphosphate (FPP) to drimenyl diphosphate. Cannot use geranylgeranyl diphosphate (GGPP) as substrate.<ref>PMID:36416740</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces showdoensis]]
[[Category: Dong LB]]
[[Category: Dong SM]]
[[Category: Pan XM]]