View source for 8zhr


==Cryo-EM structure of the full-length pAg-bound BTN2A1-BTN3A1-BTN3A2 complex==
<StructureSection load='8zhr' size='340' side='right'caption='[[8zhr]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8zhr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZHR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H6P:(2E)-4-HYDROXY-3-METHYLBUT-2-EN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>H6P</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zhr OCA], [https://pdbe.org/8zhr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zhr RCSB], [https://www.ebi.ac.uk/pdbsum/8zhr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zhr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BT3A2_HUMAN BT3A2_HUMAN] Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.<ref>PMID:21918970</ref> <ref>PMID:22767497</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Huang B]]
[[Category: Su Q]]
[[Category: Xin W]]
[[Category: Zhou Q]]