View source for 8zok


==EcGPR tetramer with catalytic intermediates==
<StructureSection load='8zok' size='340' side='right'caption='[[8zok]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8zok]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZOK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZOK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.03&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=VHF:(2~{S})-2-azanyl-5-oxidanylidene-5-phosphonooxy-pentanoic+acid'>VHF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zok OCA], [https://pdbe.org/8zok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zok RCSB], [https://www.ebi.ac.uk/pdbsum/8zok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zok ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PROA_ECOLI PROA_ECOLI] Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.[HAMAP-Rule:MF_00412]<ref>PMID:7034716</ref> <ref>PMID:7035170</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Leng Q]]
[[Category: Liu LJ]]
[[Category: Zhang T]]