View source for 8zty


==Cryo-EM structure of the Cas13a-rAcrVIA1 complex==
<StructureSection load='8zty' size='340' side='right'caption='[[8zty]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8zty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_seeligeri_serovar_1/2b_str._SLCC3954 Listeria seeligeri serovar 1/2b str. SLCC3954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZTY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zty OCA], [https://pdbe.org/8zty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zty RCSB], [https://www.ebi.ac.uk/pdbsum/8zty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zty ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CS13A_LISSS CS13A_LISSS] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. Unlike many single-component effectors, this CRISPR-Cas system targets RNA (By similarity). CRISPR clusters are transcribed from pre-CRISPR RNA (crRNA) and processed into crRNA by this protein (PubMed:27669025).[UniProtKB:P0DOC6]<ref>PMID:27669025</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Listeria seeligeri serovar 1/2b str. SLCC3954]]
[[Category: Jia N]]
[[Category: Li YL]]
[[Category: Zhang JT]]