View source for 8zua


==The complex structure of MPXV M1R and neutralizing antibody A138==
<StructureSection load='8zua' size='340' side='right'caption='[[8zua]], [[Resolution|resolution]] 3.49&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8zua]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZUA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.49&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zua OCA], [https://pdbe.org/8zua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zua RCSB], [https://www.ebi.ac.uk/pdbsum/8zua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zua ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PG095_MONPV PG095_MONPV] Component of the entry fusion complex (EFC), which consists of 11 proteins. During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.[UniProtKB:P07612]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Monkeypox virus]]
[[Category: Ge JW]]