View source for 9au7


==Human Retriever VPS35L/VPS29/VPS26C complex bound to SNX17 peptide (Composite Map)==
<StructureSection load='9au7' size='340' side='right'caption='[[9au7]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9au7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9AU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9AU7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9au7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9au7 OCA], [https://pdbe.org/9au7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9au7 RCSB], [https://www.ebi.ac.uk/pdbsum/9au7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9au7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VPS29_HUMAN VPS29_HUMAN] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).<ref>PMID:15247922</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Boesch DJ]]
[[Category: Burstein E]]
[[Category: Chen B]]
[[Category: Chen Z]]
[[Category: Fung HYJ]]
[[Category: Han Y]]
[[Category: Juneja P]]