View source for 9bfe


==Tyrocidine synthetase modules 1 and 2 crosslinked in the condensation state, complex B==
<StructureSection load='9bfe' size='340' side='right'caption='[[9bfe]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9bfe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BFE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.23&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AN1:[(7~{S},10~{a}~{R})-4-[4-[2-[2-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]ethylamino]-2-oxidanylidene-ethyl]phenyl]-1-methyl-3,5,6,7,8,9,10,10~{a}-octahydrocycloocta[d]pyridazin-7-yl]+~{N}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl]carbamate'>A1AN1</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9bfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9bfe OCA], [https://pdbe.org/9bfe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9bfe RCSB], [https://www.ebi.ac.uk/pdbsum/9bfe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9bfe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TYCA_BREPA TYCA_BREPA] In the first step of peptide synthesis this enzyme activates phenylalanine and racemizes it to the D-isomer.
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</StructureSection>
[[Category: Brevibacillus parabrevis]]
[[Category: Large Structures]]
[[Category: Burkart MD]]
[[Category: Heberlig GW]]