View source for 9btw


==Human Amylin3 Receptor in complex with Gs and cagrilintide==
<StructureSection load='9btw' size='340' side='right'caption='[[9btw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9btw]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BTW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BTW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9btw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9btw OCA], [https://pdbe.org/9btw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9btw RCSB], [https://www.ebi.ac.uk/pdbsum/9btw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9btw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAMP3_HUMAN RAMP3_HUMAN] Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.<ref>PMID:23674134</ref> <ref>PMID:9620797</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Belousoff MJ]]
[[Category: Cao J]]
[[Category: Johnson RM]]
[[Category: Sexton PM]]
[[Category: Wootten DL]]