View source for 9cs1


==E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP2==
<StructureSection load='9cs1' size='340' side='right'caption='[[9cs1]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9cs1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Photorhabdus_khanii Photorhabdus khanii] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CS1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CS1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.147&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4NE:TETRABUTYLPHOSPHONIUM'>4NE</scene>, <scene name='pdbligand=DI8:(3S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC+ACID'>DI8</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=R3W:CHLOROACETIC+ACID'>R3W</scene>, <scene name='pdbligand=UX8:(2~{S},3~{R})-2-azanyl-3-(1~{H}-indol-3-yl)-3-oxidanyl-propanoic+acid'>UX8</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cs1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cs1 OCA], [https://pdbe.org/9cs1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cs1 RCSB], [https://www.ebi.ac.uk/pdbsum/9cs1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cs1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BAMA_ECO24 BAMA_ECO24] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.[HAMAP-Rule:MF_01430]
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Photorhabdus khanii]]
[[Category: Synthetic construct]]
[[Category: Gu M]]
[[Category: Klein DJ]]
[[Category: Lu J]]
[[Category: Walker ME]]