View source for 9d47


==Atomic model of Candida albicans Fatty Acid Synthase (FAS) in complex with Palmitoyl-CoA (in vitro binding)==
<StructureSection load='9d47' size='340' side='right'caption='[[9d47]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9d47]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9D47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9D47 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PKZ:PALMITOYL-COA'>PKZ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9d47 OCA], [https://pdbe.org/9d47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9d47 RCSB], [https://www.ebi.ac.uk/pdbsum/9d47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9d47 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FAS1_CANAX FAS1_CANAX] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
__TOC__
</StructureSection>
[[Category: Candida albicans]]
[[Category: Large Structures]]
[[Category: Hasan NSM]]
[[Category: Keszei FAA]]
[[Category: Mazhab-Jafari MT]]