View source for 9d4c


==Proteasome core particle assembly intermediate Blm10:alpha-ring purified from Saccharomyces cerevisiae.==
<StructureSection load='9d4c' size='340' side='right'caption='[[9d4c]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9d4c]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9D4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9D4C FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9d4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9d4c OCA], [https://pdbe.org/9d4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9d4c RCSB], [https://www.ebi.ac.uk/pdbsum/9d4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9d4c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSA1_YEAST PSA1_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chen X]]
[[Category: Kaur M]]
[[Category: Roelofs J]]
[[Category: Walters KJ]]