View source for 9da9


==Crystal structure of GluN1/GluN2A agonist-binding domains in complex with 7CKA and glutamate==
<StructureSection load='9da9' size='340' side='right'caption='[[9da9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9da9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DA9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CKA:7-CHLOROKYNURENIC+ACID'>CKA</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9da9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9da9 OCA], [https://pdbe.org/9da9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9da9 RCSB], [https://www.ebi.ac.uk/pdbsum/9da9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9da9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NMDE1_RAT NMDE1_RAT] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Bosco J]]
[[Category: Hansen KB]]
[[Category: McClelland LJ]]
[[Category: Voronina E]]
[[Category: Yates-Hansen CK]]