View source for 9dcj


==Pentameric Structure of MERS-CoV Envelope Protein Transmembrane Domain Determined by Solid-State NMR==
<StructureSection load='9dcj' size='340' side='right'caption='[[9dcj]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9dcj]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Betacoronavirus_England_1 Betacoronavirus England 1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DCJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR,  models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dcj OCA], [https://pdbe.org/9dcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dcj RCSB], [https://www.ebi.ac.uk/pdbsum/9dcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dcj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VEMP_MERS1 VEMP_MERS1] Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis.[HAMAP-Rule:MF_04204]<ref>PMID:25733052</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Betacoronavirus England 1]]
[[Category: Large Structures]]
[[Category: Hong M]]
[[Category: Sucec I]]