View source for 9dds


==Crystal structure of human AAGAB G domain with E144K mutation==
<StructureSection load='9dds' size='340' side='right'caption='[[9dds]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9dds]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DDS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dds OCA], [https://pdbe.org/9dds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dds RCSB], [https://www.ebi.ac.uk/pdbsum/9dds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dds ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/AAGAB_HUMAN AAGAB_HUMAN] Punctate palmoplantar keratoderma type 1. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/AAGAB_HUMAN AAGAB_HUMAN] May be involved in endocytic recycling of growth factor receptors such as EGFR.<ref>PMID:23064416</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Tian Y]]
[[Category: Wang B]]
[[Category: Yin Q]]