View source for 9dg2


==PmHMGR bound to mevalonate, CoA, and NAD, buffer-exchanged to ammonium acetate environment at pH 6.7==
<StructureSection load='9dg2' size='340' side='right'caption='[[9dg2]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9dg2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DG2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dg2 OCA], [https://pdbe.org/9dg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dg2 RCSB], [https://www.ebi.ac.uk/pdbsum/9dg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dg2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas mevalonii]]
[[Category: Purohit V]]
[[Category: Rushton P]]
[[Category: Schmidt T]]
[[Category: Stauffacher CV]]
[[Category: Steussy CN]]