View source for 9dkz


==In situ microED structure of the Eosinophil major basic protein-1==
<StructureSection load='9dkz' size='340' side='right'caption='[[9dkz]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9dkz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DKZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dkz OCA], [https://pdbe.org/9dkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dkz RCSB], [https://www.ebi.ac.uk/pdbsum/9dkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dkz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRG2_HUMAN PRG2_HUMAN] Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.<ref>PMID:10913121</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bingman CA]]
[[Category: Mitchell J]]
[[Category: Mosher D]]
[[Category: Wright ER]]
[[Category: Yang JE]]