View source for 9eap


==MNV Allosteric escape mutant V339I + GCDCA==
<StructureSection load='9eap' size='340' side='right'caption='[[9eap]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9eap]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Murine_norovirus_1 Murine norovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EAP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHO:GLYCOCHENODEOXYCHOLIC+ACID'>CHO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9eap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9eap OCA], [https://pdbe.org/9eap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9eap RCSB], [https://www.ebi.ac.uk/pdbsum/9eap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9eap ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAPSD_MNV1 CAPSD_MNV1] Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulates the genomic RNA and is decorated with VP2 proteins (By similarity). Mediates virion attachment to the host cell receptor CD300LF (PubMed:27540007, PubMed:30194229).[UniProtKB:Q83884]<ref>PMID:27540007</ref> <ref>PMID:30194229</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Murine norovirus 1]]
[[Category: Sherman M]]
[[Category: Smith TJ]]