View source for 9ecm


==Structure of the human integrin alphaX transmembrane domain==
<StructureSection load='9ecm' size='340' side='right'caption='[[9ecm]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ecm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ECM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ECM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 21 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ecm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ecm OCA], [https://pdbe.org/9ecm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ecm RCSB], [https://www.ebi.ac.uk/pdbsum/9ecm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ecm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ITAX_HUMAN ITAX_HUMAN] Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Situ AJ]]
[[Category: Ulmer TS]]
[[Category: Vu HN]]