View source for 9fcn


==OPR3 loop swap variant L6(AchrOYE4) in complex with NADPH4==
<StructureSection load='9fcn' size='340' side='right'caption='[[9fcn]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9fcn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Achromobacter_sp._JA81 Achromobacter sp. JA81] and [https://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FCN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=TXP:1,4,5,6-TETRAHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE+PHOSPHATE'>TXP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fcn OCA], [https://pdbe.org/9fcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fcn RCSB], [https://www.ebi.ac.uk/pdbsum/9fcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fcn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OPR3_SOLLC OPR3_SOLLC] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.[https://www.uniprot.org/uniprot/I3V5V6_9BURK I3V5V6_9BURK] 
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</StructureSection>
[[Category: Achromobacter sp. JA81]]
[[Category: Large Structures]]
[[Category: Solanum lycopersicum]]
[[Category: Bijelic A]]
[[Category: Kerschbaumer B]]
[[Category: Macheroux P]]