View source for 9fms


==Cryo-EM structure of S. cerevisiae Rai1-Rat1-Rtt103(252-273) complex.==
<StructureSection load='9fms' size='340' side='right'caption='[[9fms]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9fms]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FMS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fms OCA], [https://pdbe.org/9fms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fms RCSB], [https://www.ebi.ac.uk/pdbsum/9fms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fms ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/XRN2_YEAST XRN2_YEAST] Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA, rRNA and small nucleolar RNA (snoRNA) precursors. May promote termination of transcription by RNA polymerase II via the recruitment of 3'-end processing factors to the poly(A) site and by the degradation of nascent RNA downstream of the poly(A) site.<ref>PMID:10805743</ref> <ref>PMID:11030620</ref> <ref>PMID:11142370</ref> <ref>PMID:11238889</ref> <ref>PMID:12769851</ref> <ref>PMID:14561886</ref> <ref>PMID:15565157</ref> <ref>PMID:16131592</ref> <ref>PMID:16598041</ref> <ref>PMID:7608167</ref> <ref>PMID:8417335</ref> <ref>PMID:9207242</ref> <ref>PMID:9384595</ref> <ref>PMID:9488433</ref> <ref>PMID:9584178</ref> <ref>PMID:9891049</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Dikunova A]]
[[Category: Noskova N]]
[[Category: Stefl R]]