View source for 9fnl


==The structure of CBM42 from Clostridium thermocellum in complex with arabinofuranosyl xylobiose (A3X) substrate molecules==
<StructureSection load='9fnl' size='340' side='right'caption='[[9fnl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9fnl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus_DSM_1313 Acetivibrio thermocellus DSM 1313]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FNL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AHR:ALPHA-L-ARABINOFURANOSE'>AHR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fnl OCA], [https://pdbe.org/9fnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fnl RCSB], [https://www.ebi.ac.uk/pdbsum/9fnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fnl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RSGI5_ACET2 RSGI5_ACET2] Anti-sigma factor for SigI5. Negatively regulates SigI5 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI5 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI5.[UniProtKB:A3DBH1]
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</StructureSection>
[[Category: Acetivibrio thermocellus DSM 1313]]
[[Category: Large Structures]]
[[Category: Hadad N]]
[[Category: Lavid N]]
[[Category: Shoham G]]
[[Category: Shoham Y]]