View source for 9foi


==Structure of human KCTD1==
<StructureSection load='9foi' size='340' side='right'caption='[[9foi]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9foi]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FOI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9foi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9foi OCA], [https://pdbe.org/9foi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9foi RCSB], [https://www.ebi.ac.uk/pdbsum/9foi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9foi ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] Scalp-ear-nipple syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.<ref>PMID:18358072</ref> <ref>PMID:19115315</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Borkowska O]]
[[Category: Bufton JC]]
[[Category: Bullock AN]]
[[Category: Burgess-Brown NA]]
[[Category: Hunt AE]]
[[Category: Manning CE]]
[[Category: Pike ACW]]
[[Category: Pinkas DM]]
[[Category: Richardson W]]
[[Category: Shrestha L]]