View source for 9fqt


==Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the apo inward-open state==
<StructureSection load='9fqt' size='340' side='right'caption='[[9fqt]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9fqt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Murine_leukemia_virus Murine leukemia virus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FQT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fqt OCA], [https://pdbe.org/9fqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fqt RCSB], [https://www.ebi.ac.uk/pdbsum/9fqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fqt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CTR1_MOUSE CTR1_MOUSE] High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.<ref>PMID:1652100</ref> <ref>PMID:1908564</ref> <ref>PMID:9174363</ref>   (Microbial infection) Acts as a receptor for the ecotropic murine retroviral leukemia virus.<ref>PMID:1908564</ref> <ref>PMID:2541919</ref> [https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin.
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Murine leukemia virus]]
[[Category: Mus musculus]]
[[Category: Bakshi S]]
[[Category: Brooke L]]
[[Category: Elkins J]]
[[Category: Pike ACW]]
[[Category: Sauer DB]]
[[Category: Stuart DI]]
[[Category: Wang D]]
[[Category: Wang S]]
[[Category: Williams E]]
[[Category: Ye M]]
[[Category: Zhou D]]