View source for 9fvc


==Crystal structure of VcSiaP in complex with a VHH antibody (VHH_VcP#1)==
<StructureSection load='9fvc' size='340' side='right'caption='[[9fvc]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9fvc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FVC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fvc OCA], [https://pdbe.org/9fvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fvc RCSB], [https://www.ebi.ac.uk/pdbsum/9fvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fvc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SIAP_VIBCH SIAP_VIBCH] Part of the tripartite ATP-independent periplasmic (TRAP) transport system SiaPQM that catalyzes unidirectional Na(+)-dependent sialic acid uptake. Binds the common sialic acid N-acetylneuraminic acid (Neu5Ac) with a high affinity.<ref>PMID:22167185</ref> <ref>PMID:22556361</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibrio cholerae]]
[[Category: Vicugna pacos]]
[[Category: Hagelueken G]]
[[Category: Schneberger N]]