View source for 9g2g


==Staphylococcus aureus MazF in complex with nanobody 5==
<StructureSection load='9g2g' size='340' side='right'caption='[[9g2g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9g2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9G2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9G2G FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8004824&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9g2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9g2g OCA], [https://pdbe.org/9g2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9g2g RCSB], [https://www.ebi.ac.uk/pdbsum/9g2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9g2g ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MAZF_STAAN MAZF_STAAN] Toxic component of a toxin-antitoxin (TA) module. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. Cleavages occur preferentially in a U-rich region with a consensus sequence of 5'-[ACG]UU[ACG]-3' in single-stranded RNA (By similarity).
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</StructureSection>
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Haesaerts S]]
[[Category: Loris R]]
[[Category: Prolic-Kalinsek M]]
[[Category: Zorzini V]]