View source for 9gbk


==Blm10-20S proteasome complex from pre1-1==
<StructureSection load='9gbk' size='340' side='right'caption='[[9gbk]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9gbk]] is a 19 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GBK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.39&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gbk OCA], [https://pdbe.org/9gbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gbk RCSB], [https://www.ebi.ac.uk/pdbsum/9gbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gbk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSB6_YEAST PSB6_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Dohmen RJ]]
[[Category: Hoeckendorff J]]
[[Category: Kayser F]]
[[Category: Mark E]]
[[Category: Ramos PC]]
[[Category: Wendler P]]