View source for 9geg


==Entamoeba histolytica Gal/GalNAc lectin heavy chain residues 808-992 in the presence of GalNAc==
<StructureSection load='9geg' size='340' side='right'caption='[[9geg]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9geg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Entamoeba_histolytica Entamoeba histolytica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GEG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9geg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9geg OCA], [https://pdbe.org/9geg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9geg RCSB], [https://www.ebi.ac.uk/pdbsum/9geg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9geg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HGL1_ENTH1 HGL1_ENTH1] Lectin which binds galactose and N-acetyl-D-galactosamine of host glycoproteins and thus mediates adhesion to host cells (Probable). Mediates adherence to host colonic mucins, an essential step for pathogenic tissue invasion (Probable).<ref>PMID:12142490</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Entamoeba histolytica]]
[[Category: Large Structures]]
[[Category: Gerard SF]]
[[Category: Higgins MK]]