View source for 9gfm


==CryoEM structure of the human INO80 core-nucleosome complex state N-7==
<StructureSection load='9gfm' size='340' side='right'caption='[[9gfm]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9gfm]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GFM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gfm OCA], [https://pdbe.org/9gfm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gfm RCSB], [https://www.ebi.ac.uk/pdbsum/9gfm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gfm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IN80B_HUMAN IN80B_HUMAN] Induces growth and cell cycle arrests at the G1 phase of the cell cycle.<ref>PMID:15556297</ref>   Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.<ref>PMID:15556297</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Aggarwal P]]
[[Category: Hopfner KP]]
[[Category: Sharma M]]