View source for 9ggq


==E.coli gyrase holocomplex with cleaved chirally wrapped 217 bp DNA fragment and moxifloxacin==
<StructureSection load='9ggq' size='340' side='right'caption='[[9ggq]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ggq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_phage_Mu Escherichia phage Mu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GGQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ggq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ggq OCA], [https://pdbe.org/9ggq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ggq RCSB], [https://www.ebi.ac.uk/pdbsum/9ggq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ggq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GYRA_ECOLI GYRA_ECOLI] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051842</ref> <ref>PMID:18642932</ref> <ref>PMID:19965760</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia phage Mu]]
[[Category: Large Structures]]
[[Category: Ghilarov D]]
[[Category: Heddle JG]]
[[Category: Pabis M]]