View source for 9gj2


==Crystal structure of human cathepsin S produced in insect cells in complex with ketoamide 13b==
<StructureSection load='9gj2' size='340' side='right'caption='[[9gj2]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9gj2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GJ2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gj2 OCA], [https://pdbe.org/9gj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gj2 RCSB], [https://www.ebi.ac.uk/pdbsum/9gj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gj2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Falke S]]
[[Category: Guenther S]]
[[Category: Karnicar K]]
[[Category: Lindic N]]
[[Category: Meents A]]
[[Category: Reinke PYA]]
[[Category: Sekirnik A]]
[[Category: Turk D]]
[[Category: Usenik A]]