View source for 9gnv


==Human SENP5 in complex with SUMO1==
<StructureSection load='9gnv' size='340' side='right'caption='[[9gnv]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9gnv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GNV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AYE:PROP-2-EN-1-AMINE'>AYE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gnv OCA], [https://pdbe.org/9gnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gnv RCSB], [https://www.ebi.ac.uk/pdbsum/9gnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gnv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SENP5_HUMAN SENP5_HUMAN] Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.<ref>PMID:16608850</ref> <ref>PMID:16738315</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Li Y]]
[[Category: Reverter D]]
[[Category: Sanchez-Alba L]]