View source for 9goc


==Crystal structure of DPP9 Ser730Ala in complex with sulphostin.==
<StructureSection load='9goc' size='340' side='right'caption='[[9goc]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9goc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GOC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1INE:[azanyl-[(3~{S})-3-azanyl-2-oxidanylidene-piperidin-1-yl]phosphoryl]sulfamic+acid'>A1INE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9goc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9goc OCA], [https://pdbe.org/9goc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9goc RCSB], [https://www.ebi.ac.uk/pdbsum/9goc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9goc ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/DPP9_HUMAN DPP9_HUMAN] Idiopathic pulmonary fibrosis. 
== Function ==
[https://www.uniprot.org/uniprot/DPP9_HUMAN DPP9_HUMAN] Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Fehr L]]
[[Category: Geiss-Friedlander R]]
[[Category: Hellerschmied D]]
[[Category: Huber R]]
[[Category: Kaiser M]]
[[Category: Kaschani F]]
[[Category: Lammens A]]
[[Category: Najdzion M]]
[[Category: Podlesainski D]]
[[Category: Sewald L]]
[[Category: Tabak WWA]]
[[Category: Verhoef CJA]]
[[Category: Zolg S]]