View source for 9gon


==Crystal structure of DPP9 in complex with sulphostin==
<StructureSection load='9gon' size='340' side='right'caption='[[9gon]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9gon]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GON FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1INF:azanyl-oxidanylidene-(sulfoamino)phosphanium'>A1INF</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gon OCA], [https://pdbe.org/9gon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gon RCSB], [https://www.ebi.ac.uk/pdbsum/9gon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gon ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/DPP9_HUMAN DPP9_HUMAN] Idiopathic pulmonary fibrosis. 
== Function ==
[https://www.uniprot.org/uniprot/DPP9_HUMAN DPP9_HUMAN] Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Fehr L]]
[[Category: Geiss-Friedlander R]]
[[Category: Hellerschmied D]]
[[Category: Huber R]]
[[Category: Kaiser M]]
[[Category: Kaschani F]]
[[Category: Lammens A]]
[[Category: Najdzion M]]
[[Category: Podlesainski D]]
[[Category: Sewald L]]
[[Category: Tabak WWA]]
[[Category: Verhoef CJA]]
[[Category: Zolg S]]