View source for 9gra


==Homodimer of BACH1 BTB domain in complex with 2-Methyl-2,4-pentanediol==
<StructureSection load='9gra' size='340' side='right'caption='[[9gra]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9gra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GRA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gra OCA], [https://pdbe.org/9gra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gra RCSB], [https://www.ebi.ac.uk/pdbsum/9gra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gra ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BACH1_HUMAN BACH1_HUMAN] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Goretzki B]]
[[Category: Gutmann S]]
[[Category: Hinniger A]]