View source for 9hfr


==Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer without a ligand==
<StructureSection load='9hfr' size='340' side='right'caption='[[9hfr]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hfr]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HFR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HFR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hfr OCA], [https://pdbe.org/9hfr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hfr RCSB], [https://www.ebi.ac.uk/pdbsum/9hfr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hfr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CDAC1_HUMAN CDAC1_HUMAN] Catalyzes the deamination of cytidine and deoxycytidine into uridine and deoxyuridine, respectively (PubMed:26945630). May play an important role in testicular development and spermatogenesis (PubMed:16955368).<ref>PMID:16955368</ref> <ref>PMID:26945630</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bochtler M]]
[[Category: Czarnocki-Cieciura M]]
[[Category: Kanai T]]
[[Category: Lountos G]]
[[Category: Rathore I]]
[[Category: Skowronek K]]
[[Category: Slyvka A]]
[[Category: Wang Z]]
[[Category: Wlodawer A]]
[[Category: Yang R]]