View source for 9hih


==Mouse IL-2 fused to S4B6 Fab fragment==
<StructureSection load='9hih' size='340' side='right'caption='[[9hih]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hih]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HIH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hih OCA], [https://pdbe.org/9hih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hih RCSB], [https://www.ebi.ac.uk/pdbsum/9hih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hih ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IL2_MOUSE IL2_MOUSE] Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Rattus norvegicus]]
[[Category: Blaha J]]
[[Category: Skorepa O]]
[[Category: Vanek O]]