View source for 9hjs


==Crystal structure of human geranylgeranyl diphosphate synthase mutant R235C==
<StructureSection load='9hjs' size='340' side='right'caption='[[9hjs]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hjs]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HJS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hjs OCA], [https://pdbe.org/9hjs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hjs RCSB], [https://www.ebi.ac.uk/pdbsum/9hjs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hjs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GGPPS_HUMAN GGPPS_HUMAN] Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Giladi M]]
[[Category: Haitin Y]]
[[Category: Yehia R]]