View source for 9hkr


==NMR structure of the C-terminal domain of the human SPAG1 protein==
<StructureSection load='9hkr' size='340' side='right'caption='[[9hkr]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HKR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR,  models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hkr OCA], [https://pdbe.org/9hkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hkr RCSB], [https://www.ebi.ac.uk/pdbsum/9hkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hkr ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/SPAG1_HUMAN SPAG1_HUMAN] Primary ciliary dyskinesia. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/SPAG1_HUMAN SPAG1_HUMAN] May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity.<ref>PMID:11517287</ref> <ref>PMID:1299558</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chagot ME]]
[[Category: Quinternet M]]