View source for 9hpa


==Structure of A16/G9 (vaccinia virus) in complex with VHH D07 and VHH E12==
<StructureSection load='9hpa' size='340' side='right'caption='[[9hpa]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hpa]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Western_Reserve Vaccinia virus Western Reserve] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HPA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hpa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hpa OCA], [https://pdbe.org/9hpa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hpa RCSB], [https://www.ebi.ac.uk/pdbsum/9hpa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hpa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PG143_VACCW PG143_VACCW] Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation).<ref>PMID:16352530</ref> <ref>PMID:22278246</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vaccinia virus Western Reserve]]
[[Category: Vicugna pacos]]
[[Category: Guardado-Calvo P]]
[[Category: Meola A]]
[[Category: Vernuccio R]]